The Fractalkine/CX3CR1 System Regulates Beta Cell Function and Insulin Secretion

Here, we demonstrate that the fractalkine(FKN)/CX3CR1 system represents a previously undescribed regulatory mechanism for pancreatic islet beta cell function and insulin secretion. CX3CR1 KO mice exhibited a marked defect in glucose and GLP1-stimulated insulin secretion, and this defect was also obs...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lee, Yun Sok, Morinaga, Hidetaka, Kim, Jane J., Lagakos, William, Taylor, Susan, Keshwani, Malik, Perkins, Guy, Dong, Hui, Kayali, Ayse G., Sweet, Ian R., Olefsky, Jerrold
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717389/
https://ncbi.nlm.nih.gov/pubmed/23582329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker