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The Fractalkine/CX3CR1 System Regulates Beta Cell Function and Insulin Secretion
Here, we demonstrate that the fractalkine(FKN)/CX3CR1 system represents a previously undescribed regulatory mechanism for pancreatic islet beta cell function and insulin secretion. CX3CR1 KO mice exhibited a marked defect in glucose and GLP1-stimulated insulin secretion, and this defect was also obs...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717389/ https://ncbi.nlm.nih.gov/pubmed/23582329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.03.001 |
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