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Chronic injection of pansomatostatin agonist ODT8-SST differentially modulates food intake and decreases body weight gain in lean and diet-induced obese rats

The aim of this study was to investigate the central actions of the stable pansomatostatin peptide agonist, ODT8-SST on body weight. ODT8-SST or vehicle was acutely (1 μg/rat) injected or chronically infused (5 μg/rat/d, 14d) intracerebroventricularly and daily food intake, body weight and compositi...

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Detalhes bibliográficos
Main Authors: Stengel, Andreas, Coskun, Tamer, Goebel-Stengel, Miriam, Craft, Libbey S., Alsina-Fernandez, Jorge, Wang, Lixin, Rivier, Jean, Taché, Yvette
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717146/
https://ncbi.nlm.nih.gov/pubmed/21315111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2011.01.006
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