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Central administration of pansomatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats

BACKGROUND: Activation of brain somatostatin receptors (sst(1-5)) with the stable pan-sst(1-5) somatostatin agonist, ODT8-SST blocks acute stress and central corticotropin-releasing factor (CRF)-mediated activation of endocrine adrenal sympathetic responses. Brain CRF signaling is involved in delayi...

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Main Authors: STENGEL, A., GOEBEL-STENGEL, M., WANG, L., LUCKEY, A., HU, E., RIVIER, J., TACHÉ, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117963/
https://ncbi.nlm.nih.gov/pubmed/21569179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2011.01721.x
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