Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity

BACKGROUND: The adipokine leptin and its receptor are expressed in the heart, and leptin has been shown to promote cardiomyocyte hypertrophy in vitro. Obesity is associated with hyperleptinemia and hypothalamic leptin resistance as well as an increased risk to develop cardiac hypertrophy and heart f...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Leifheit-Nestler, Maren, Wagner, Nana-Maria, Gogiraju, Rajinikanth, Didié, Michael, Konstantinides, Stavros, Hasenfuss, Gerd, Schäfer, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717024/
https://ncbi.nlm.nih.gov/pubmed/23841921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-170
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados