Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis

BACKGROUND: Sirtuin 1 (Sirt1) is a nuclear enzyme from the class III histone deacetylases that modulates gene expression and is involved in bone and cartilage remodeling. The goal of our study was to evaluate Sirt1 activity in peripheral blood mononuclear cells in patients with osteoarthritis in com...

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Autori principali: Wendling, Daniel, Abbas, Wasim, Godfrin-Valnet, Marie, Guillot, Xavier, Khan, Kashif Aziz, Cedoz, Jean-Pierre, Baud, Lucile, Prati, Clément, Herbein, Georges
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716931/
https://ncbi.nlm.nih.gov/pubmed/23844973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-10
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