Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis

BACKGROUND: Sirtuin 1 (Sirt1) is a nuclear enzyme from the class III histone deacetylases that modulates gene expression and is involved in bone and cartilage remodeling. The goal of our study was to evaluate Sirt1 activity in peripheral blood mononuclear cells in patients with osteoarthritis in com...

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Détails bibliographiques
Auteurs principaux: Wendling, Daniel, Abbas, Wasim, Godfrin-Valnet, Marie, Guillot, Xavier, Khan, Kashif Aziz, Cedoz, Jean-Pierre, Baud, Lucile, Prati, Clément, Herbein, Georges
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716931/
https://ncbi.nlm.nih.gov/pubmed/23844973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-10
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