Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis

BACKGROUND: Sirtuin 1 (Sirt1) is a nuclear enzyme from the class III histone deacetylases that modulates gene expression and is involved in bone and cartilage remodeling. The goal of our study was to evaluate Sirt1 activity in peripheral blood mononuclear cells in patients with osteoarthritis in com...

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Main Authors: Wendling, Daniel, Abbas, Wasim, Godfrin-Valnet, Marie, Guillot, Xavier, Khan, Kashif Aziz, Cedoz, Jean-Pierre, Baud, Lucile, Prati, Clément, Herbein, Georges
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716931/
https://ncbi.nlm.nih.gov/pubmed/23844973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-10
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