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Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway
OBJECTIVE: The tumor necrosis factor (TNF) and the cellular NF-κB pathway protein IKKβ play important roles in various cellular processes such as cell proliferation, survival, differentiation, and apoptosis. A heat shock protein 90 inhibitor, 17-DMAG, can induce apoptosis of some tumor cells. This s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716826/ https://ncbi.nlm.nih.gov/pubmed/23635099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-8-70 |
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