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TCC: an R package for comparing tag count data with robust normalization strategies

BACKGROUND: Differential expression analysis based on “next-generation” sequencing technologies is a fundamental means of studying RNA expression. We recently developed a multi-step normalization method (called TbT) for two-group RNA-seq data with replicates and demonstrated that the statistical met...

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Bibliografiske detaljer
Main Authors: Sun, Jianqiang, Nishiyama, Tomoaki, Shimizu, Kentaro, Kadota, Koji
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716788/
https://ncbi.nlm.nih.gov/pubmed/23837715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-219
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