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Empowering scFv with effector cell functions for improved anticancer therapeutics

Single chain variable fragment (scFv) constructs have been an important source of high affinity reagents to target cancer cells. Including an immunoglobulin Fc-binding domain can empower scFvs and other tumor antigen-binding proteins with immune effector cell functions and hence significantly increa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Zhang, Hongtao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716736/
https://ncbi.nlm.nih.gov/pubmed/23894701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24439
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