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Empowering scFv with effector cell functions for improved anticancer therapeutics
Single chain variable fragment (scFv) constructs have been an important source of high affinity reagents to target cancer cells. Including an immunoglobulin Fc-binding domain can empower scFvs and other tumor antigen-binding proteins with immune effector cell functions and hence significantly increa...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716736/ https://ncbi.nlm.nih.gov/pubmed/23894701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24439 |
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