Plasma Total Ghrelin and Leptin Levels in Human Narcolepsy and Matched Healthy Controls: Basal Concentrations and Response to Sodium Oxybate

STUDY OBJECTIVES: Narcolepsy is caused by a selective loss of hypocretin neurons and is associated with obesity. Ghrelin and leptin interact with hypocretin neurons to influence energy homeostasis. Here, we evaluated whether human hypocretin deficiency, or the narcolepsy therapeutic agent sodium oxy...

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Bibliographic Details
Main Authors: Donjacour, Claire E. H. M., Pardi, Daniel, Aziz, N. Ahmad, Frölich, Marijke, Roelfsema, Ferdinand, Overeem, Sebastiaan, Pijl, Hanno, Lammers, Gert Jan
Format: Artigo
Language:Inglês
Published: American Academy of Sleep Medicine 2013
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New Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716671/
https://ncbi.nlm.nih.gov/pubmed/23946710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.2924
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