Plasma Total Ghrelin and Leptin Levels in Human Narcolepsy and Matched Healthy Controls: Basal Concentrations and Response to Sodium Oxybate

STUDY OBJECTIVES: Narcolepsy is caused by a selective loss of hypocretin neurons and is associated with obesity. Ghrelin and leptin interact with hypocretin neurons to influence energy homeostasis. Here, we evaluated whether human hypocretin deficiency, or the narcolepsy therapeutic agent sodium oxy...

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Autors principals: Donjacour, Claire E. H. M., Pardi, Daniel, Aziz, N. Ahmad, Frölich, Marijke, Roelfsema, Ferdinand, Overeem, Sebastiaan, Pijl, Hanno, Lammers, Gert Jan
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Sleep Medicine 2013
Matèries:
New Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716671/
https://ncbi.nlm.nih.gov/pubmed/23946710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.2924
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