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Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation
Inactive DNA methyltransferase (DNMT) 3B splice isoforms are associated with changes in DNA methylation, yet the mechanisms by which they act remain largely unknown. Using biochemical and cell culture assays, we show here that the inactive DNMT3B3 and DNMT3B4 isoforms bind to and regulate the activi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716610/ https://ncbi.nlm.nih.gov/pubmed/23894490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069486 |
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