Histone Deacetylase Inhibitors Interact with Melanoma Differentiation Associated-7/Interleukin-24 to Kill Primary Human Glioblastoma Cells

We presently demonstrate that histone deacetylase inhibitors (HDACIs) enhance toxicity of melanoma differentiation-associated gene-7/interleukin 24 (mda-7/IL-24) in invasive primary human glioblastoma multiforme (GBM) cells. Additionally, a method is described to augment the efficacy of adenoviral d...

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Autors principals: Hamed, Hossein A., Yacoub, Adly, Park, Margaret A., Archer, Kellie, Das, Swadesh K., Sarkar, Devanand, Grant, Steven, Fisher, Paul B., Dent, Paul
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716321/
https://ncbi.nlm.nih.gov/pubmed/23661648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086553
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