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Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a novel cytokine displaying selective apoptosis-inducing activity in transformed cells without harming normal cells. The present studies focused on defining the mechanism(s) by which a GST-MDA-7 fusion protein inhibits cell s...

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Detalhes bibliográficos
Main Authors: Yacoub, Adly, Park, Margaret A., Gupta, Pankaj, Rahmani, Mohammed, Zhang, Guo, Hamed, Hossein, Hanna, David, Sarkar, Devanand, Lebedeva, Irina V., Emdad, Luni, Sauane, Moira, Vozhilla, Nicollaq, Spiegel, Sarah, Koumenis, Costas, Graf, Martin, Curiel, David T., Grant, Steven, Fisher, Paul B., Dent, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204355/
https://ncbi.nlm.nih.gov/pubmed/18281515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2166
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