Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a novel cytokine displaying selective apoptosis-inducing activity in transformed cells without harming normal cells. The present studies focused on defining the mechanism(s) by which a GST-MDA-7 fusion protein inhibits cell s...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yacoub, Adly, Park, Margaret A., Gupta, Pankaj, Rahmani, Mohammed, Zhang, Guo, Hamed, Hossein, Hanna, David, Sarkar, Devanand, Lebedeva, Irina V., Emdad, Luni, Sauane, Moira, Vozhilla, Nicollaq, Spiegel, Sarah, Koumenis, Costas, Graf, Martin, Curiel, David T., Grant, Steven, Fisher, Paul B., Dent, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204355/
https://ncbi.nlm.nih.gov/pubmed/18281515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2166
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