Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a novel cytokine displaying selective apoptosis-inducing activity in transformed cells without harming normal cells. The present studies focused on defining the mechanism(s) by which a GST-MDA-7 fusion protein inhibits cell s...

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Hlavní autoři: Yacoub, Adly, Park, Margaret A., Gupta, Pankaj, Rahmani, Mohammed, Zhang, Guo, Hamed, Hossein, Hanna, David, Sarkar, Devanand, Lebedeva, Irina V., Emdad, Luni, Sauane, Moira, Vozhilla, Nicollaq, Spiegel, Sarah, Koumenis, Costas, Graf, Martin, Curiel, David T., Grant, Steven, Fisher, Paul B., Dent, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204355/
https://ncbi.nlm.nih.gov/pubmed/18281515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2166
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