Overexpression of H1 Calponin in Osteoblast Lineage Cells Leads to a Decrease in Bone Mass by Disrupting Osteoblast Function and Promoting Osteoclast Formation

H1 calponin (CNN1) is known as a smooth muscle-specific, actin-binding protein which regulates smooth muscle contractive activity. Although previous studies have shown that CNN1 has effect on bone, the mechanism is not well defined. To investigate the role of CNN1 in maintaining bone homeostasis, we...

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Bibliographic Details
Main Authors:	Su, Nan, Chen, Maomao, Chen, Siyu, Li, Can, Xie, Yangli, Zhu, Ying, Zhang, Yaozong, Zhao, Ling, He, Qifen, Du, Xiaolan, Chen, Di, Chen, Lin
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3716280/ https://ncbi.nlm.nih.gov/pubmed/23044709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1778
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Overexpression of H1 Calponin in Osteoblast Lineage Cells Leads to a Decrease in Bone Mass by Disrupting Osteoblast Function and Promoting Osteoclast Formation

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