Loss of menin in osteoblast lineage affects osteocyte–osteoclast crosstalk causing osteoporosis

During osteoporosis bone formation by osteoblasts is reduced and/or bone resorption by osteoclasts is enhanced. Currently, only a few factors have been identified in the regulation of bone integrity by osteoblast-derived osteocytes. In this study, we show that specific disruption of menin, encoded b...

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Vydáno v:Cell Death Differ
Hlavní autoři: Liu, Peng, Lee, Sooyeon, Knoll, Jeanette, Rauch, Alexander, Ostermay, Susanne, Luther, Julia, Malkusch, Nicole, Lerner, Ulf H, Zaiss, Mario M, Neven, Mona, Wittig, Rainer, Rauner, Martina, David, Jean-Pierre, Bertolino, Philippe, Zhang, Chang X, Tuckermann, Jan P
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384024/
https://ncbi.nlm.nih.gov/pubmed/28106886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.165
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