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Human Organic Cation Transporters 1 (SLC22A1), 2 (SLC22A2), and 3 (SLC22A3) as Disposition Pathways for Fluoroquinolone Antimicrobials

Fluoroquinolones (FQs) are important antimicrobials that exhibit activity against a wide range of bacterial pathogens and excellent tissue permeation. They exist as charged molecules in biological fluids, and thus, their disposition depends heavily on active transport and facilitative diffusion. A r...

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Main Authors: Mulgaonkar, Aditi, Venitz, Jürgen, Gründemann, Dirk, Sweet, Douglas H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716151/
https://ncbi.nlm.nih.gov/pubmed/23545524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02289-12
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