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Clearance of Thrombin from Circulation in Rabbits by High-affinity Binding Sites on Endothelium: POSSIBLE ROLE IN THE INACTIVATION OF THROMBIN BY ANTITHROMBIN III
The clearance of (125)I-thrombin and diisopropylphosphoryl-(125)I-thrombin (DIP-thrombin) from the circulation in rabbits was studied. When given either intraarterially or intravenously, DIP-thrombin, which is active-site blocked, was ∼90% cleared from the circulation by 1 min, the time of earliest...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1980
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC371606/ https://ncbi.nlm.nih.gov/pubmed/6255009 |
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