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Effect of a heparan sulphate with high affinity for antithrombin III upon inactivation of thrombin and coagulation factor Xa.

The kinetics of inhibition of human alpha-thrombin and coagulation Factor Xa by antithrombin III were examined under pseudo-first-order reaction conditions as a function of the concentration of heparan sulphate with high affinity for antithrombin III. The maximum observed second-order rate constant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scully, M F, Ellis, V, Shah, N, Kakkar, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133317/
https://ncbi.nlm.nih.gov/pubmed/2529852
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