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Clearance of Thrombin from Circulation in Rabbits by High-affinity Binding Sites on Endothelium: POSSIBLE ROLE IN THE INACTIVATION OF THROMBIN BY ANTITHROMBIN III

The clearance of (125)I-thrombin and diisopropylphosphoryl-(125)I-thrombin (DIP-thrombin) from the circulation in rabbits was studied. When given either intraarterially or intravenously, DIP-thrombin, which is active-site blocked, was ∼90% cleared from the circulation by 1 min, the time of earliest...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lollar, Pete, Owen, Whyte G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 1980
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC371606/
https://ncbi.nlm.nih.gov/pubmed/6255009
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