Quantitative PCR for Detection of Shigella Improves Ascertainment of Shigella Burden in Children with Moderate-to-Severe Diarrhea in Low-Income Countries

Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, wi...

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Detalhes bibliográficos
Main Authors: Lindsay, Brianna, Ochieng, John B., Ikumapayi, Usman N., Toure, Aliou, Ahmed, Dilruba, Li, Shan, Panchalingam, Sandra, Levine, Myron M., Kotloff, Karen, Rasko, David A., Morris, Carolyn R., Juma, Jane, Fields, Barry S., Dione, Michel, Malle, Dramane, Becker, Stephen M., Houpt, Eric R., Nataro, James P., Sommerfelt, Halvor, Pop, Mihai, Oundo, Joe, Antonio, Martin, Hossain, Anowar, Tamboura, Boubou, Stine, O. Colin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716050/
https://ncbi.nlm.nih.gov/pubmed/23536399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02713-12
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