Quantitative PCR for Detection of Shigella Improves Ascertainment of Shigella Burden in Children with Moderate-to-Severe Diarrhea in Low-Income Countries

Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, wi...

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Hauptverfasser: Lindsay, Brianna, Ochieng, John B., Ikumapayi, Usman N., Toure, Aliou, Ahmed, Dilruba, Li, Shan, Panchalingam, Sandra, Levine, Myron M., Kotloff, Karen, Rasko, David A., Morris, Carolyn R., Juma, Jane, Fields, Barry S., Dione, Michel, Malle, Dramane, Becker, Stephen M., Houpt, Eric R., Nataro, James P., Sommerfelt, Halvor, Pop, Mihai, Oundo, Joe, Antonio, Martin, Hossain, Anowar, Tamboura, Boubou, Stine, O. Colin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Epidemiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716050/
https://ncbi.nlm.nih.gov/pubmed/23536399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02713-12
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