Quantitative PCR for Detection of Shigella Improves Ascertainment of Shigella Burden in Children with Moderate-to-Severe Diarrhea in Low-Income Countries

Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity of current diagnostic and surveillance methods. We used a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59 months from the Gambia, Mali, Kenya, and Bangladesh, wi...

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Main Authors: Lindsay, Brianna, Ochieng, John B., Ikumapayi, Usman N., Toure, Aliou, Ahmed, Dilruba, Li, Shan, Panchalingam, Sandra, Levine, Myron M., Kotloff, Karen, Rasko, David A., Morris, Carolyn R., Juma, Jane, Fields, Barry S., Dione, Michel, Malle, Dramane, Becker, Stephen M., Houpt, Eric R., Nataro, James P., Sommerfelt, Halvor, Pop, Mihai, Oundo, Joe, Antonio, Martin, Hossain, Anowar, Tamboura, Boubou, Stine, O. Colin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
Epidemiology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716050/
https://ncbi.nlm.nih.gov/pubmed/23536399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02713-12
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