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Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies

Heparin-like oligosaccharides mediate numerous important biological interactions, of which many are implicated in various diseases. Synthetic improvements are central to the development of such oligosaccharides as therapeutics and, in addition, there are no methods to elucidate the pharmacokinetics...

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Detalhes bibliográficos
Main Authors: Hansen, Steen U., Miller, Gavin J., Cole, Claire, Rushton, Graham, Avizienyte, Egle, Jayson, Gordon C., Gardiner, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715853/
https://ncbi.nlm.nih.gov/pubmed/23828390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3016
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