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Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies

Heparin-like oligosaccharides mediate numerous important biological interactions, of which many are implicated in various diseases. Synthetic improvements are central to the development of such oligosaccharides as therapeutics and, in addition, there are no methods to elucidate the pharmacokinetics...

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Bibliografiska uppgifter
Huvudupphovsmän: Hansen, Steen U., Miller, Gavin J., Cole, Claire, Rushton, Graham, Avizienyte, Egle, Jayson, Gordon C., Gardiner, John M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715853/
https://ncbi.nlm.nih.gov/pubmed/23828390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3016
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