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Translocation of PKC by Yessotoxin in an in Vitro Model of Alzheimer’s Disease with Improvement of Tau and β-Amyloid Pathology

[Image: see text] Yessotoxin is a marine phycotoxin that induces motor alterations in mice after intraperitoneal injection. In primary cortical neurons, yessotoxin treatment induced a caspase-independent cell death with an IC(50) of 4.27 nM. This neurotoxicity was enhanced by 4,4′-diisothiocyanatost...

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Main Authors: Alonso, Eva, Vale, Carmen, Vieytes, Mercedes R., Botana, Luis M.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2013
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715845/
https://ncbi.nlm.nih.gov/pubmed/23527608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400018y
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