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Retinoic Acid-Elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein
[Image: see text] Retinoic acid (RA)-elicited signaling has been shown to play critical roles in development, organogenesis, and the immune response. RA regulates expression of Alzheimer’s disease (AD)-related genes and attenuates amyloid pathology in a transgenic mouse model. In this study, we inve...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American
Chemical Society
2013
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715835/ https://ncbi.nlm.nih.gov/pubmed/23530929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400039s |
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