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Modulation by Syk of Bcl-2, calcium and the calpain-calpastatin proteolytic system in human breast cancer cells

Syk is a 72 kDa non-receptor tyrosine kinase that is best characterized in hematopoietic cells. While Syk is pro-tumorigenic in some cancer cell types, it also has been reported as a negative regulator of metastatic cell growth in others. An examination of the RelA (p65) subunit of NF-κB expressed i...

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Библиографические подробности
Главные авторы: Fei, Bei, Yu, Shuai, Geahlen, Robert L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715600/
https://ncbi.nlm.nih.gov/pubmed/23684705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.05.010
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