KEAP1 Is a Redox Sensitive Target That Arbitrates the Opposing Radiosensitive Effects of Parthenolide in Normal and Cancer Cells

Elevated oxidative stress is observed more frequently in cancer cells than in normal cells. It is therefore expected that additional exposure to a low level of reactive oxygen species (ROS) will push cancer cells toward death, whereas normal cells might maintain redox homeostasis through adaptive an...

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Autors principals: Xu, Yong, Fang, Fang, Miriyala, Sumitra, Crooks, Peter A., Oberley, Terry D., Chaiswing, Luksana, Noel, Teresa, Holley, Aaron K., Zhao, Yanming, Kiningham, Kelley K., St Clair, Daret K., St Clair, William H.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715565/
https://ncbi.nlm.nih.gov/pubmed/23674500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4297
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