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The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-κB inhibition and enhanced by the presence of PTEN

Parthenolide has been shown to have anti-inflammatory and antitumor properties. However, whether and how parthenolide enhances tumor sensitivity to radiation therapy are unknown. In this study, we show that inhibition of the nuclear factor-κB (NF-κB) pathway is a common mechanism for the radiosensit...

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Détails bibliographiques
Auteurs principaux: Sun, Yulan, St Clair, Daret K., Fang, Fang, Warren, Graham W., Rangnekar, Vivek M., Crooks, Peter A., St Clair, William H.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627774/
https://ncbi.nlm.nih.gov/pubmed/17876045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-0186
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