Discovery and Characterization of BlsE, a Radical S-Adenosyl-L-methionine Decarboxylase Involved in the Blasticidin S Biosynthetic Pathway

BlsE, a predicted radical S-adenosyl-L-methionine (SAM) protein, was anaerobically purified and reconstituted in vitro to study its function in the blasticidin S biosynthetic pathway. The putative role of BlsE was elucidated based on bioinformatics analysis, genetic inactivation and biochemical char...

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Detalhes bibliográficos
Main Authors: Feng, Jun, Wu, Jun, Dai, Nan, Lin, Shuangjun, Xu, H. Howard, Deng, Zixin, He, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715490/
https://ncbi.nlm.nih.gov/pubmed/23874663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068545
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