Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity

Defining the mechanisms of Mycobacterium tuberculosis (Mtb) persistence in the host macrophage and identifying mycobacterial factors responsible for it are keys to better understand tuberculosis pathogenesis. The emerging picture from ongoing studies of macrophage deactivation by Mtb suggests that i...

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Main Authors: Sun, Jim, Singh, Vijender, Lau, Alice, Stokes, Richard W., Obregón-Henao, Andrés, Orme, Ian M., Wong, Dennis, Av-Gay, Yossef, Hmama, Zakaria
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715411/
https://ncbi.nlm.nih.gov/pubmed/23874203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003499
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