Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity

Defining the mechanisms of Mycobacterium tuberculosis (Mtb) persistence in the host macrophage and identifying mycobacterial factors responsible for it are keys to better understand tuberculosis pathogenesis. The emerging picture from ongoing studies of macrophage deactivation by Mtb suggests that i...

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Detalhes bibliográficos
Main Authors: Sun, Jim, Singh, Vijender, Lau, Alice, Stokes, Richard W., Obregón-Henao, Andrés, Orme, Ian M., Wong, Dennis, Av-Gay, Yossef, Hmama, Zakaria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715411/
https://ncbi.nlm.nih.gov/pubmed/23874203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003499
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