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Mechanism of HIV-1 Virion Entrapment by Tetherin

Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent enveloped viral particles from the surface of infected cells. However, the mechanisms underlying virion retention have not yet been fully delineated. Here, we employ biochemical assays and engineered tetherin protein...

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Detalhes bibliográficos
Main Authors: Venkatesh, Siddarth, Bieniasz, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715405/
https://ncbi.nlm.nih.gov/pubmed/23874200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003483
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