APOE-ε2 and APOE-ε4 Correlate with Increased Amyloid Accumulation in Cerebral Vasculature

The APOE ε4 allele correlates with increased risk of Alzheimer disease (AD) and increased parenchymal amyloid plaques. We tested how the APOE genotype correlated with cerebral amyloid angiopathy (CAA) by analyzing 371 brains for parenchymal and meningeal CAA in 4 brain regions (frontal, parietal, te...

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Auteurs principaux: Nelson, Peter T., Pious, Nina M., Jicha, Gregory A., Wilcock, Donna M., Fardo, David A., Estus, Steven, Rebeck, G. William
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715146/
https://ncbi.nlm.nih.gov/pubmed/23771217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31829a25b9
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