Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers

OBJECTIVE: The apolipoprotein E (APOE) ε4 allele enhances cerebral accumulation of β-amyloid (Aβ) and is a major risk factor for sporadic Alzheimer’s disease (AD). We hypothesized that HIV-associated neurocognitive disorders (HAND) would be associated with the APOE ε4 genotype and cerebral Aβ deposi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Soontornniyomkij, Virawudh, Moore, David J., Gouaux, Ben, Soontornniyomkij, Benchawanna, Tatro, Erick T., Umlauf, Anya, Masliah, Eliezer, Levine, Andrew J., Singer, Elyse J., Vinters, Harry V., Gelman, Benjamin B., Morgello, Susan, Cherner, Mariana, Grant, Igor, Achim, Cristian L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576852/
https://ncbi.nlm.nih.gov/pubmed/23018443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835a117c
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