Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders

FK506 binding protein (FKBP)-51 and FKBP52 act as molecular chaperones to control glucocorticoid receptor (GR) sensitivity. Dysregulation of proteins involved in GR-mediated signaling can lead to maladaptive stress response and aging-related cognitive decline. As HIV infection is related to chronic...

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Main Authors: Soontornniyomkij, Virawudh, Everall, Ian P., Moore, David J., Gouaux, Ben, Tatro, Erick T., Gospodarev, Vadim, Masliah, Eliezer, Yin, Nicole S., Vinters, Harry V., Achim, Cristian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374917/
https://ncbi.nlm.nih.gov/pubmed/22234543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-011-0076-8
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