Thyrotropin-releasing Hormone Stimulation of Adrenocorticotropin Production by Mouse Pituitary Tumor Cells in Culture

ACTH-producing mouse pituitary tumor cells in culture (AtT-20/NYU-1 cells) were found to have binding sites for thyrotropin-releasing hormone (TRH). These putative receptors bound TRH with high affinity; the apparent equilibrium dissociation constant was 3.7 nM. The affinity of the receptors for a s...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Gershengorn, Marvin C., Arevalo, Carlos O., Geras, Elizabeth, Rebecchi, Mario J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1980
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6251109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109792
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