Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor
Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and low...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2012-10-01
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| Serier: | Frontiers in Endocrinology |
| Fag: | |
| Online adgang: | http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00120/full |
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