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Propeptides of eukaryotic proteases encode histidines to exploit organelle pH for regulation
Eukaryotic cells maintain strict control over protein secretion, in part by using the pH gradient maintained within their secretory pathway. How eukaryotic proteins evolved from prokaryotic orthologs to exploit the pH gradient for biological functions remains a fundamental question in cell biology....
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Federation of American Societies for Experimental Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714588/ https://ncbi.nlm.nih.gov/pubmed/23585398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-226886 |
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