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Mapping the functional domains of TCblR/CD320, the receptor for cellular uptake of transcobalamin-bound cobalamin

The membrane receptor TCblR/CD320 binds transcobalamin (TC) saturated with vitamin B(12) [cobalamin (Cbl)] and mediates cellular uptake of the vitamin. The specificity of TC for Cbl and of the receptor for TC-Cbl ensures efficient uptake of Cbl into cells. The high-affinity interaction of TCblR with...

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Hlavní autoři: Jiang, Wenxia, Nakayama, Yasumi, Sequeira, Jeffrey M., Quadros, Edward V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714585/
https://ncbi.nlm.nih.gov/pubmed/23603833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-230185
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