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Mapping the functional domains of TCblR/CD320, the receptor for cellular uptake of transcobalamin-bound cobalamin
The membrane receptor TCblR/CD320 binds transcobalamin (TC) saturated with vitamin B(12) [cobalamin (Cbl)] and mediates cellular uptake of the vitamin. The specificity of TC for Cbl and of the receptor for TC-Cbl ensures efficient uptake of Cbl into cells. The high-affinity interaction of TCblR with...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Federation of American Societies for Experimental Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714585/ https://ncbi.nlm.nih.gov/pubmed/23603833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-230185 |
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