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The prevalence of loss of imprinting of H19 and IGF2 at birth

Imprinted genes are monoallelically expressed according to the parent of origin and are critical for proper placental and embryonic development. Disruption of methylation patterns at imprinted loci resulting in loss of imprinting (LOI) may lead to serious imprinting disorders (e.g., Beckwith-Wiedema...

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Библиографические подробности
Главные авторы: Rancourt, Rebecca C., Harris, Holly R., Barault, Ludovic, Michels, Karin B.
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714582/
https://ncbi.nlm.nih.gov/pubmed/23620526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225284
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