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Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

Differentially methylated sequences associated with imprinted genes are proposed to control genomic imprinting. A 2-kb region located 5′ to the imprinted mouse H19 gene is hypermethylated on the inactive paternal allele throughout development. To determine whether this differentially methylated doma...

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Bibliografske podrobnosti
Main Authors: Thorvaldsen, Joanne L., Duran, Kristen L., Bartolomei, Marisa S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC317260/
https://ncbi.nlm.nih.gov/pubmed/9851976
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