Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
Differentially methylated sequences associated with imprinted genes are proposed to control genomic imprinting. A 2-kb region located 5′ to the imprinted mouse H19 gene is hypermethylated on the inactive paternal allele throughout development. To determine whether this differentially methylated doma...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9851976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.23.3693 |
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