Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

Differentially methylated sequences associated with imprinted genes are proposed to control genomic imprinting. A 2-kb region located 5′ to the imprinted mouse H19 gene is hypermethylated on the inactive paternal allele throughout development. To determine whether this differentially methylated doma...

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Εκδόθηκε σε:	Genes Dev
Κύριοι συγγραφείς:	Thorvaldsen, Joanne L., Duran, Kristen L., Bartolomei, Marisa S.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Cold Spring Harbor Laboratory Press 1998
Θέματα:	Research Paper
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9851976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.23.3693
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