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Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism

Folic acid is an essential component of 1-carbon metabolism, which generates methyl groups for DNA methylation. Disruption of genomic imprinting leads to biallelic expression which may affect disease susceptibility possibly reflected in high levels of S-adenosyl-homocysteine (SAH) and low levels of...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Tserga, Aggeliki, Binder, Alexandra M., Michels, Karin B.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690385/
https://ncbi.nlm.nih.gov/pubmed/28778973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601214RR
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