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B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3(+) regulatory T cells
Although T cell activation has been classically described to require distinct, positive stimulation signals that include B7-1 (CD80) and B7-2 (CD86) costimulation, overriding suppression signals that avert immune-mediated host injury are equally important. How these opposing stimulation and suppress...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714566/ https://ncbi.nlm.nih.gov/pubmed/23744647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0313118 |
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