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Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

The key role played by of Fgf10 during early lung development is clearly illustrated in Fgf10 knockout mice, which exhibit complete lung agenesis. However, Fgf10 is continuously expressed throughout lung development suggesting extended as well as additional roles for FGF10 at later stages of lung or...

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Autores principales: Ramasamy, Suresh K., Mailleux, Arnaud A., Gupte, Varsha, V., Mata, Francisca, Sala, Frédéric G., Veltmaat, Jacqueline M., Del Moral, Pierre M., De Langhe, Stijn, Parsa, Sara, Kelly, Lisa K., Kelly, Robert, Keshet, Eli, Minoo, Parviz, Warburton, David, Bellusci, Savério
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714306/
https://ncbi.nlm.nih.gov/pubmed/17560563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.033
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